In these conditions, the cause of aldosteronism is made by recognizing the underlying disease. The Differential Diagnosis of Secondary Hyperaldosteronism is sorted out by the presence or absence of HTN and the presence of other obvious diagnoses (CHF/hepatic dysfunction, dehydration, pregnancy, etc). Source: Halperin F., Alexander E., Robert Dluhy R. Endotext: Chapter 23 – Aldosterone Excess July 15 2010.Note: dopamine, heparin and ANP (Atrial Natriuretic Peptide) inhibit the production of Aldosterone. Potassium and ACTH stimulate Aldosterone production.
Secondary aldosteronism is more common than primary aldosteronism. It is caused by
anything that leads to excess aldosterone, other than a disorder of the adrenal glands.
It could be caused by anything that decreases blood flow to the kidneys, decreases
blood pressure, or lowers sodium levels, i.e. anything that increases the activation
of the renin-